New Course=> PHA 250 Functional Genomics: from Bench to Bedside


PHA250: Functional Genomics: from Bench to Bedside
CRN: 84839
Spring 2012
Tuesdays/Thursdays 9:00-10:30am
Location: Tupper 2133

Instructor of Record (IOR): David Segal

COURSE GOALS AND ORGANIZATION: The purpose of the course is to familiarize
students with topics in Functional Genomics, with an emphasis on clinical
relevance and applications (e.g., genetic variation and disease, cancer
therapeutics, and biomarker discovery). Specific topics that will be covered
include detection of altered gene sequences, and measurements of the changes
in chromatin and RNA that occur in human diseases. Technologies that will be
covered include DNA and RNA microarrays and next generation sequencing
methods. Other topics will include data visualization and interpretation.
The overall goal of the class is to provide an overview of the cutting edge
technologies currently being developed in basic science laboratories, and
illustrate how these technologies can be used to improve public health.
Students will actively participate in group presentations. There will be
four guest lecturers who will add breadth to the program.

PREREQUISITE: Permission of Instructor
UNITS: 3 U (letter grade)


Author: Jonathan Eisen

I am an evolutionary biologist and a Professor at U. C. Davis. (see my lab site here). My research focuses on the origin of novelty (how new processes and functions originate). To study this I focus on sequencing and analyzing genomes of organisms, especially microbes and using phylogenomic analysis

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