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PHA250: Functional Genomics: from Bench to Bedside
Location: Tupper 2133
Instructor of Record (IOR): David Segal
COURSE GOALS AND ORGANIZATION: The purpose of the course is to familiarize
students with topics in Functional Genomics, with an emphasis on clinical
relevance and applications (e.g., genetic variation and disease, cancer
therapeutics, and biomarker discovery). Specific topics that will be covered
include detection of altered gene sequences, and measurements of the changes
in chromatin and RNA that occur in human diseases. Technologies that will be
covered include DNA and RNA microarrays and next generation sequencing
methods. Other topics will include data visualization and interpretation.
The overall goal of the class is to provide an overview of the cutting edge
technologies currently being developed in basic science laboratories, and
illustrate how these technologies can be used to improve public health.
Students will actively participate in group presentations. There will be
four guest lecturers who will add breadth to the program.
PREREQUISITE: Permission of Instructor
UNITS: 3 U (letter grade)