Well, this seems like seriously big news in the microbiome world: Fecal Tx Flunks IBD Test but Optimism High. Charles Bankhead reports on results presented at the “Digestive Disease Week” meeting. At the meeting Paul Moayyedi from McMaster University reported that a clinical trial of fecal microbial transplants (FMT for short) was stopped midway through the trial due to “lack of efficacy”. More specifically Bankhead reports
The investigators found no significant differences in the primary outcome or any of the secondary outcomes, which included the Inflammatory Bowel Disease Questionnaire and the EQ5D health status assessment
The researcher seems enthusiastic about FMT still but certainly this means that FMT for IBD is not going to be like FMT for CDiff (just wanted to make sure I got in a lot of abbreviations there). I am sure there will be much more to come on FMT and it would be good to see more detail on what was presented at the meeting (a paper, or poster, or such). But for now, this hopefully will temper some of the overselling of FMT that is going around (e.g., Overselling the microbiome award: Mercola/Perlmutter on fecal transplants for severe neurological dysfunction).
Related posts:
- Posts tageed “overselling the microbiome“
- Posts tagged “overselling the microbiome award“
- Posts tagged fecal transplants
- Posts tagged fecal bacteriotherapy
- Transfaunation and Fecal Transplants: What Goes Around Comes Around, Literally and Figuratively
- #PLoSOne paper on the “horse #microbiome” and colitis; wonder if they will study ‘poo tea’
- Human microbiome story of the month: OpenBiome fecal bank for fecal transplants
- Just in time for #ASM2013 – FDA adding regulations for fecal transplants #microbiome
- Must read microbiome paper of the month: defined microbioata treatment of Cdiff infections
- Got poo?: Clinical trial on fecal transplants (aka fecal bacteriotherapy) to treat C. difficile infections
- More (you know you wanted it) on fecal transplants and the microbiome
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