Just a quick post here. There is a nice review by Monya Baker on de novo genome assembly in Nature Methods: De novo genome assembly: what every biologist should know : Nature Methods : Nature Publishing Group. It is currently freely available though not sure if that is permanent or not …
Love the start which quotes my colleague Ian Korf
Asked how mature the field of genome assembly is, Ian Korf at the University of California, Davis, compares it to a teenager with great capabilities. “It’s got bold assertions about what it can do, but at the same time it’s making embarrassing mistakes,” he says
The paper is definitely worth a look …
Jonathan Eisen's Lab 