New paper in mBIO of potential interest from Lance Price et al.: Staphylococcus aureus CC398: Host Adaptation and Emergence of Methicillin Resistance in Livestock. For those not in the know, mBIO is a relatively new Open Access journal from the American Society for Microbiology. The paper discusses genomic studies of MRSA which has led the authors to conclude that antibiotic use in animals may contribute to the rise and spread of superbugs in people.
|From here. Maximum-parsimony tree of the 89 CC398 isolates (including ST398SO385) based on 4,238 total SNPs, including 1,102 parsimony-informative SNPs with a CI of 0.9591. Clades and groups of importance are labeled in a hierarchical fashion to facilitate description in the text. The tree was rooted with clade I based on an iterative selection process that identified this group as the most ancestral (see Materials and Methods). COO, country of origin; AT, Austria; BE, Belgium; CA, Canada; CH, Switzerland; CN, China; DE, Germany; DK, Denmark; ES, Spain; FI, Finland; FR, France; GF, French Guiana; HU, Hungary; IT, Italy; NL, The Netherlands; PE, Peru; PL, Poland; PT, Portugal; SI, Slovenia; US, United States; P, pig; H, human; R, horse; T, turkey; B, bovine; MET, methicillin susceptibility; R, resistant; S, susceptible.|
The figure above is the only figure in the main text of the paper. There are others in supplemental information which seems a bit strange to me – why put anything in supplemental information when the paper is only released online? Or at least have thumbnail images for all figures in the main text …
Anyway, the paper and press release got picked up by many newsy places. See for example:
- Pig-to-Human ‘Superbug’ May Be Due to Animal Antibiotics (US News)
- MRSA Staph Strain Developed Drug Resistance in Your Burger (US News)
- How Using Antibiotics In Animal Feed Creates Superbugs (NPR blog)
- MRSA in Livestock May Spread to Humans (ABC news)
- Staph Turns into Drug-Resistant Superbug on Farms (SciAm blog)
UPDATE 2/21 5:30 PM: an alternative (and much more pleasing) press release from ASM is here.