Eisen Lab Blog

#PLOS Hub for Biodiversity – soon to be retired

Just got the email below.

Dear Subscriber,

We are writing to you as someone who is a registered user on PLOS Hubs: Biodiversity to let you know that we will shortly be retiring it.

Thousands of Biodiversity articles, including research from all fields plus associated magazine content, have now been published across the PLOS journals. With this healthy level of ongoing activity, the community has outgrown the original need for the Hub, which was created to give greater visibility to their previously widely dispersed content.

Rest assured that we are developing more powerful tools for our journals to help those working in this community rapidly find and filter Open Access content, and continue to seek novel ways to re-organize and present it for discussion.

If you have any specific questions please email our user services team.

Best wishes
The PLOS Publications and Products Team

From io9: Even more microbial art "Bacterial communities swarm into gorgeous works of art"

Another quick post.  There is an article in io9 about art from Eshel Ben-Jacob and his beloved Paenibacillus: Bacterial communities swarm into gorgeous works of art.  Some pretty cool images there of these organisms grown on plates and then artistically enhanced.

Definitely worth a look.

Must read of the week: For Better Science Meetings, Invite an Artist The Finch and Pea

Art by @artologica in my living room

This is just such a good idea: For Better Science Meetings, Invite an Artist | The Finch and Pea.  Michelle Banks, also known as artologica, writing at The Finch and the Pea, goes through a detailed argument, with examples, of why one should invite artists to science meetings.

I have been inspired by Michele at many meetings.  And I have been inspired by her art with a science theme (see for example the posts listed below).

I have written a bit here and there about the mixing of science and art.  See for example

But if you read one thing about science and art – read Michele’s new post.  Or, even better, start inviting artists to any science conference you have any role in.

Annual Notification: How to File Whistleblower Reports (#UCDavis)

Seemed worth wide distribution:

2013_Whistleblower_Poster_Revised_by_OP.pdf

At #UCDavis June 24: Mini-symposium on cancer genetics and admixture mapping-

MINI-SYMPOSIUM ON

CANCER GENETICS AND ADMIXTURE MAPPING

SPONSORED BY UC DAVIS HUMAN GENETICS AND GENOMICS

FOCUS GROUP AND THE CHIBCHA CONSORTIUM

Date: June 24, 2013

Location: GBSF 1005

CHIBCHA_flyer_061413_FINAL.pdf

ADVANCE Blog Notes: Interesting article by Mary Ann Mason at Slate.Com "In the Ivory Tower, Men Only"

There is a really interesting article at Slate.Com from Mary Ann Mason, the author of “Do Babies Matter” which I have written about here before.  The post is titled “In the Ivory Tower, Men Only“.  The post tells some of the background behind the book and discusses issues about graduate school, post doctoral positions, applying for faculty jobs and more.   The article also has some very good guidance for universities that would like to level the playing field:

We all know what structural changes would help to level the playing field in all of these careers and they are quite similar: paid family leave for both mothers and fathers, especially for childbirth, a flexible workplace, a flexible career track, a re-entry policy, pay equity reviews, child care assistance, dual career assistance. Those universities and corporations who have actively created these policies have found an advantage in recruitment and retention. For instance, at Berkeley, after enacting several new policies to benefit parents, including paid teaching leaves for fathers, job satisfaction scored much higher among parents, and more babies are being born to assistant professors.

Some good guidance for some of the activities at UC Davis as part of the ADVANCE program in which I am involved. And she ends by recommending

It is time for women to “lean in” and demand family policies that will at least give them a fighting chance to have both a successful career and babies.

I agree.  But it is also time for men to do the same.  The more that men also support and demand such policies the quicker things will change.

Lab meeting. June 18th 2013

Nicholas Bokulich will be presenting for tomorrow’s lab meeting.
We will be meeting from 1:30 to 3pm in room 4202 of the Genome Center.

ADVANCE Reading of the Day: Sylvia Earle, Women in Japan and the Gulf, Spaceflight

Quick post here … Some news stories and posts I am checking out today in relation to the UC Davis ADVANCE project in which I am involved.

How Open Are You? Part 1: Metrics to Measure Openness and Free Availability of Publications

For many many years I have been raising a key questions in relation to open access publishing – how can we measure how open someone’s publications are.  Ideally we would have a way of measuring this in some sort of index.  A few years ago I looked around and asked around and did not find anything out there of obvious direct relevance to what I wanted so I started mapping out ways to do this.

When Aaron Swartz died I started drafting some ideas on this topic.  Here is what I wrote (in January 2013) but never posted:

With the death of Aaron Swartz on Friday there has been much talk of people posting their articles online (a short term solution) and moving more towards openaccess publishing (a long term solution).  One key component of the move to more openaccess publishing will be assessing people on just how good a job they are doing of sharing their academic work.

I have looked around the interwebs to see if there is some existing metric for this and I could not find one.  So I have decided to develop one – which I call the Swartz Openness Index (SOI).

Let A = # of objects being assessed (could be publications, data sets, software, or all of these together). 

Let B = # of objects that are released to the commons with a broad, open license. 

A simple (and simplistic) metric could be simply 

OI = B / A


This is a decent start but misses out on the degree of openness of different objects. So a more useful metric might be the one below.

A and B as above. 

Let C = # of objects available free of charge but not openly 

OI = ( B + (C/D) ) / A  

where D is the “penalty” for making material in C not openly available


This still seems not detailed enough.  A more detailed approach might be to weight diverse aspects of the openness of the objects.  Consider for example the “Open Access Spectrum.”  This has divided objects (publications in this case) into six categories in terms of potential openness: reader rights, reuse rights, copyrights, author posting rights, automatic posting, and machine readability.  And each of these is given different categories that assess the level of openness.  Seems like a useful parsing in ways.  Alas, since bizarrely the OAS is released under a somewhat restrictive CC BY-NC-ND  license I cannot technically make derivatives of it.  So I will not.  Mostly because I am pissed at PLoS and SPARC for releasing something in this way.  Inane.

But I can make my own openness spectrum.

And then I stopped writing because I was so pissed off at PLOS and SPARC for making something like this and then restricting it’s use.  I had a heated discussion with people from PLOS and SPARC about this but not sure if they updated their policy.  Regardless, the concept of an Openness Index of some kind fell out of my head after this buzzkill.  And it only just now came back to me. (Though I note – I did not find the Draft post I made until AFTER I wrote the rest of this post below … ).

To get some measure of openness in publications maybe a simple metric would be useful.  Something like the following

  • P = # of publications
  • A = # of fully open access papers
  • OI = Openness index

A simple OI would be

  • OI = 100 * A/P
However, one might want to account for relative levels of openness in this metric.  For example
  • AR = # of papers with a open but somewhat restricted license
  • F = # of papers that are freely available but not with an open license
  • C = some measure of how cheap the non freely available papers are
And so on.
Given that I am not into library science myself and not really familiar with playing around with this type of data I thought a much simpler metric would be to just go to Pubmed (which of course works only for publications in the arenas covered by Pubmed).
From Pubmed one can pull out some simple data. 
  • # of publications (for a person or Institution)
  • # of those publications in PubMed Central (a measure of free availability)
Thus one could easily measure the “Pubmed Central” index as
PMCI = 100 * (# publications in PMC / # of publications in Pubmed)
Some examples of the PMCI for various authors including some bigger names in my field, and some people I have worked with.
            Name                        #s                 PMCI    
Eisen JA
224/269  
83.2
Eisen MB 
76/104
73.1
Collins FS
192/521
36.8
Lander ES
160/377
42.4
Lipman DJ
58/73
79.4
Nussinov R
170/462
36.7
Mardis E
127/187
67.9
Colwell RR
237/435
54.5
Varmus H
165/408
40.4
Brown PO
164/234
70.1
Darling AE
20/27
74.0
Coop G
23/39
59.0
Salzberg SL
107/162
61.7
Venter JC
53/237
22.4
Ward NL
24/58
41.4
Fraser CM
78/262
29.8
Quackenbush J
95/225
42.2
Ghedin E
47/82
57.3
Langille MG
10/14
71.4

And so on.  Obviously this is of limited value / accuracy in many ways.  Many papers are freely available but not in Pubmed Central.  Many papers are not covered by Pubmed or Pubmed Central.  Times change, so some measure of recent publications might be better than measuring all publications.  Author identification is challenging (until systems like ORCID get more use).  And so on.

Another thing one can do with Pubmed is to identify papers with free full text available somewhere (not just in PMC).  This can be useful for cases where material is not put into PMC for some reason.  And then with a similar search one can narrow this to just the last five years.  As openaccess has become more common maybe some people have shifted to it more and more over time (I have — so this search should give me a better index).

Lets call the % of publications with free full text somewhere the “Free Index” or FI.  Here are the values for the same authors.

Name
PMC 
%
Pudmed 
PMCI 
Free
%
Pubmed
5 years
FI – 5 
Free
%
Pubmed
All
FI-ALL
Eisen JA
224/269
83.2
178/180
98.9
237
88.1
Eisen MB 
76/104
73.1
32/34
94.1
83 79.8
Collins FS
192/521
36.8
104/128
81.3
263 50.5
Lander ES
160/377
42.4
78/104
75.0
200 53.1
Lipman DJ
58/73
79.4
20/22
90.9
59 80.8
Mardis E
127/187
67.9
90/115
78.3
135 72.2
Colwell RR
237/435
54.5
31/63
49.2
258 59.3
Varmus H
165/408
40.4
21/28
75.0
206 50.5
Brown PO
164/234
70.1
20/21
95.2
185 79.0
Darling AE
20/27
74.0
18/21
85.7
21 77.8
Coop G
23/39
59.0
16/20
80.0
28 71.8
Salzberg SL
107/162
61.7
54/58
93.1
128 79.0
Venter JC
53/237
22.4
20/33
60.6
85 35.9
Ward NL
24/58
41.4
18/27
66.6
30 51.7
Fraser CM
78/262
29.8
9/13
69.2
109 41.6
Quackenbush J
95/225
42.2
54/75
72.0
131 58.2
Ghedin E
47/82
57.3
30/36
83.3
56 68.3
Langille MG
10/14
71.4
11/13
84.6
11 78.6

Very happy to see that I score very well for the last five years. 180 papers in Pubmed.  178 of them with free full text somewhere that Pubmed recognizes. The large number of publications comes mostly from genome reports in the open access journals Standards in Genomic Sciences and Genome Announcements.  But most of my non genome report papers are also freely available.

I think in general it would be very useful to have measures of the degree of openness.  And such metrics should take into account sharing of other material like data, methods, etc.  In a way this could be a form of the altmetric calculations going on.

But before going any further I decided to look again into what has been done in this area. When I first thought of doing this a few years ago I searched and asked around and did not see much of anything.  (Although I do remember someone out there – maybe Carl Bergstrom – saying there were some metrics that might be relevant – but can’t figure out who / what this information in the back of my head is).

So I decided to do some searching anew.  And lo and behold there was something directly relevant. There is a paper in the Journal of Librarianship and Scholarly Communication called: The Accessibility Quotient: A New Measure of Open Access.  By Mathew A. Willmott, Katharine H. Dunn, and Ellen Finnie Duranceau from MIT.

Full Citation: Willmott, MA, Dunn, KH, Duranceau, EF. (2012). The Accessibility Quotient: A New Measure of Open Access. Journal of Librarianship and Scholarly Communication 1(1):eP1025. http://dx.doi.org/10.7710/2162-3309.1025
Here is the abstract:

Abstract
INTRODUCTION The Accessibility Quotient (AQ), a new measure for assisting authors and librarians in assessing and characterizing the degree of accessibility for a group of papers, is proposed and described. The AQ offers a concise measure that assesses the accessibility of peer-reviewed research produced by an individual or group, by incorporating data on open availability to readers worldwide, the degree of financial barrier to access, and journal quality. The paper reports on the context for developing this measure, how the AQ is calculated, how it can be used in faculty outreach, and why it is a useful lens to use in assessing progress towards more open access to research.
METHODS Journal articles published in 2009 and 2010 by faculty members from one department in each of MIT’s five schools were examined. The AQ was calculated using economist Ted Bergstrom’s Relative Price Index to assess affordability and quality, and data from SHERPA/RoMEO to assess the right to share the peer-reviewed version of an article.
RESULTS The results show that 2009 and 2010 publications by the Media Lab and Physics have the potential to be more open than those of Sloan (Management), Mechanical Engineering, and Linguistics & Philosophy.
DISCUSSION Appropriate interpretation and applications of the AQ are discussed and some limitations of the measure are examined, with suggestions for future studies which may improve the accuracy and relevance of the AQ.
CONCLUSION The AQ offers a concise assessment of accessibility for authors, departments, disciplines, or universities who wish to characterize or understand the degree of access to their research output, capturing additional dimensions of accessibility that matter to faculty.

I completely love it.  After all. it is directly related to what I have been thinking about and, well, they actually did some systematic analysis of their metrics.  I hope more things like this come out and are readily available for anyone to calculate.  Just how open someone is could be yet another metric used to evaluate them …

And then I did a little more searching and found the following which also seem directly relevant

So – it is good to see various people working on such metrics.  And I hope there are more and more.
Anyway – I know this is a bit incomplete but I simply do not have time right now to turn this into a full study or paper and I wanted to get these ideas out there.  I hope someone finds them useful …

Another week – another microbial art project

The use of microbes in art projects continues to spread.  Here is another example: Bioluminescent art: Beautiful bacteria glow in the dark | MNN – Mother Nature Network.  The article discusses the Bioglyphs project which involved “some microbiology training, imagination, and a lot of petri dishes.”  Definitely worth checking out …