My microbiome talk at #FOGM15 – the perils (and fun I guess) of redoing one’s talk at the last minute

Just got back from the Future of Genomic Medicine 2015 meeting where I gave a talk about microbiomes.  My original plan was to talk about the need for evolutionary and ecological approaches to microbiome studies but I changed my mind a few days before the meeting and decided to switch to talking more about citizen microbiology.  I did this because the meeting has a lot of people who think about digital and wearable technology and public engagement in the audience and it just seemed like a good chance to introduce them to the growing personal/citizen microbiology movement.

To help prep for my talk I emailed some colleagues who work on Citizen Microbiology (including a few in my lab like Jenna Lang and David Coil) and asked them if they had any slides I could pilfer.  And then I started drafting an outline of my talk (I draft all my talks by hand with pen and paper). Here are my handwritten notes

 I realized I would not likely be able to focus enough at home to work on the talk so I kind of waited until heading down to San Diego on Wednesday (talk was on Friday).

I got in pretty late and worked a little on my talk before going to bed.  I also emailed the organizers of the meeting to say I was changing the topic of my talk a bit and asked if they could change the online program which they did.  Eric Topol in response to my saying I wanted to talk about citizen microbiology and personal microbiomes very wisely suggested that I talk about my vision for the future of microbiome research.  I (lamely) had been so focused on Citizen Microbiology that I had not been thinking much about the bigger picture.  But once he suggested this notion my talk really congealed (in my head and on paper at least).  It is interesting to me how one simple suggestion from someone with vision and perspective can transform one’s thought process so much …

Anyway, the next day I headed over to the meeting venue (by the beach – life is rough in San Diego).  I got there in time to hear Francis Collins’ talk.  I spent the day sitting outside in the outdoor tent viewing area, pondering my talk and listening to the talks of others. Lots and lots of interesting things presented there.  More about this later I hope.  Anyway – that evening I worked on my talk some more, headed down to the hotel bar for a bit and then worked on my talk some more.  And eventually went to sleep.  Friday I spent much of the AM working on my talk in the outdoor tent (while listening to the talks though this time not watching them on the screen since I was a bit too far away from it).  And voila – only 30 minutes before the PM session was to begin I finished the prep.  I do not like to do this normally but I just felt like my talk would be much better if I re-conceived it and I had to make all new slides pretty much for the whole talk (other than the few I pilfered from colleagues).

I note – I was talking after Marty Blaser and figured I would not have to introduce the human microbiome at all and also that he would give an overview of the risks that come from disturbing the microbiome.  Anyway, I gave my talk, and recorded the slideshow with Camtasia.  Below are my slides, the video slideshow, and a Storify of the Tweets others posted during my talk.
As is frequently the case, afterwards I felt I was too rushed and that it was not the best talk I have ever given. But that being said, I like the general outline and some of the concepts and figured I should share, warts and all. My biggest regret after talks which I have rushed a bit in preparing is that I usually do not do a great job in mentioning who did all the work I refer to. I try to put people’s pictures and names on all slides and references but I don’t always get this done in time and I worry I screwed this up for a few topics here. Oh well, life goes on …

Here is a slideshow with Audio (which I recorded via Camtasia)

Here is the Slideshare posting of my slides

Thoughts on Citizen Microbiology and upcoming session at #ASM2013

I am sitting on a Southwest Airlines flight heading to Denver for the American Society for Microbiology 2013 meeting. At 3 PM today I am scheduled to co-chair (with David Coil from my lab) a session on “Citizen Microbiology” (well the full title is Citizen Microbiology: Enhancing Microbiology Education and Research with the Help of the Public). The schedule of the session is at the bottom of this post but it promises to be very interesting and exciting (no bias here at all).

As far as I know, this is the first session ever on “Citizen Microbiology” at a large meeting of any kind. We held a small workshop at UC Davis in January of 2012 on Citizen Microbiology but that was quite small. I note – I use a very broad definition for Citizen Microbiology including basically any project that engages the public in some way to participate in a research project relating to microbes. This is the perfect time to have such a session at a large meeting and the ASM General Meeting is an ideal setting. There are a series of converging forces that makes this timing ideal including:

There is a growing appreciation of microbes and the role they play on the planet. Some of this appreciation is broad – covering all microbes – all the time – everywhere. But much of it is due to a growing interest in the microbes closer to us – those that live in and on us (the human microbiome) – those that live in and on plants and animals and other organisms we care about – and those that live in the places where we spend much of our time (the microbes of the built environment). I mean – come on – everyone is talking about fecal transplants now in public – in cover stories of the NY Times Magazine and in Ted talks.

  • Technological and scientific advances have made it possible to better sample the microbes found in any particular location. Clearly, DNA sequencing technology and associated analytical tools are a central component of these advances, but other factors are important too. 
  • The world is becoming more and more digital which makes the sharing of information (which is key to Citizen Science) easier and better. And social media has made it easier to communicate and discuss actions like Citizen Microbiology. 
  • Citizen Science is growing by leaps and bounds in other areas (e.g., check out http://www.scistarter.com). 
  • Crowdsourcing (not the same thing as Citizen Science – more on this another time perhaps) is also growing in leaps and bounds. 
  • Crowdfunding is providing new ways to fund scientific activities. 
  • Sensors of all kinds are getting cheaper and easier to use and are being deployed widely. 
  • Many people are becoming more and more interesting in recording information about themselves and sharing it with others. 
  • The “open science” movement is making the literature, software, methods and data and more available to everyone with no or few restrictions thus allowing for more people in diverse environments to become engaged in research. 
  • Microbiology education and outreach is spreading with some great journalists and diverse other sources of information including hundreds of microbiology blogs and many other forms of social media being used. 

These are but a few of the reasons why I believe the time is right for Citizen Microbiology. But there are also what I would call somewhat negative reasons why the time is right too. These include 

  • Germophobia is rampant and fueled by media hype and marketing forces. 
  • We have done, and continue to do, serious harm to our microbial world. Antibiotics are overused. Antimicrobials are in everything. More and more children and missing out on vaginal birth. And so on 
  • Although our understanding of the importance of microbes is everywhere, there are also many who are overselling what we know – claiming that probiotics will cure all ailments for example. 
  • Some information about microbes that is out there on the web is, well, less that ideal 
  • The ethics of engaging the public in studies of microbes are not fully appreciated by some and not completely understood by most. 

So this is both an exciting and a critical time for microbes and microbiology. And I hope that this session will not only help launch the field of Citizen Microbiology, but will help get everyone to think about the bigger issues and how to move the field forward in the right directions. For there is so much we need to do and think about including

  • Ethics 
  • Funding 
  • Openness and sharing 
  • Visualization 
  • Analysis tools 
  • Communication 
  • Outreach 

And of course – the people at the session are not the only ones engaged in Citizen Microbiology or related activities (see a list we made a while back here). If you are doing a project please post something about it here. And if you are not doing a Citizen Microbiology project – well – why not? Get your act together.

Anyway – got to put away the computer as we land in Denver soon and I will rush off to the conference center, hopefully on time, to chair this exciting session. And I hope to see you there or have you follow online (check out the Twitter hash tag #ASM2013). And keep your eyes open for more excitement in this area.

————————-
Today’s session at ASM 2013:

(Division W Lecture) Authentic Research for Novice Scientists: Phage Discovery and Genomics by Undergraduate Students
Graham Hatfull;
Univ. of Pittsburgh, Pittsburgh, PA.

Understanding Human Influence on Microbial Distribution Patterns in the United States: A Citizen Science Approach
G. Barguil Colares1, J. Marcell1, D. Smith1,2, J. A. Eisen3, J. Gilbert1,2;
1Argonne Natl. Lab., Lemont, IL, 2Univ. of Chicago, IL, 3UC Davis, Davis, CA.

The Home MIcrobiome Project: Learning the Lessons of Citizen Science and Communication
J. A. Gilbert, D. Smith;
Argonne Natl. Lab., Lemont, IL.

The New National Lab: How Citizen Science is Transforming American Research
Darlene Cavalier;
Sci. Starter, Sci. Cheerleader, Philadelphia, PA.

Sequencing the Human Microbiome with Citizen Science
Z. Apte1, J. Richman2, W. Ludington3;
1uBiome, Inc, San Francisco, CA, 2Oxford Univ., Oxford, UNITED KINGDOM, 3Univ. of California, Berkeley, Berkeley, CA.

The American Gut Project: Challenges and opportunities for crowdsourcingmicrobial ecology
Antonio Gonzalez Peña;
Univ Colorado at Boulder, Boulder, CO.

Public Science in Private Places: A Study of the Microbial Ecology of One Thousand Houses in Fifty States and Five Countries
Rob Dunn;
NC State Univ., Raleigh, NC.


UPDATE: Notes from the Session Added 5/23

Here are some notes from the meeting:
Meeting Report: ASM 2013 in Denver, Day 1
ASM 2013, Day 1: From Oceans to Guts
Citizens doing Science, or Science on Citizens? (ASM 2013: Post 1)
Symbionticism: ASM 2013 LINKS
Storify by SPONCH

My storify embedded below

Come all ye Citizen Microbiologists – to Denver 5/19 for ASM Meeting – abstracts due 1/15

This is going to rock.  Citizen microbiology – highlighted at the American Society for Microbiology Annual Meeting in Denver in May.  The details on the session are below.  Sunday May 19 at the American Society for Microbiology General Meeting in Denver.  If you are interested in attending Register here.  If you work on some aspect of Citizen Microbiology please consider submitting an abstract for a talk or poster. The deadline is January 15.  We will highlight ALL accepted abstracts in some way both during the session and in blogs, tweets, interviews, etc.  So please consider participating.
Citizen Microbiology: Enhancing Microbiology Education and Research with the Help of the Public OralAbstract Image
3:00 p.m.- 5:30 p.m.
Conveners:
JONATHAN EISEN; Univ. of California-Davis, Davis, CA
DAVID COIL; Univ. of California-Davis, Davis, CA
Invited Speakers:
GRAHAM HATFULL; Univ. of Pittsburgh, Pittsburgh, PA
   Carski Foundation Distinguished Undergraduate Teaching Award and Division W Lecturer
DARLENE CAVALIER; Sci. Starter, Sci. Cheerleader, Philadelphia, PA
ROB DUNN; North Carolina State Univ., Raleigh, NC
Description:
Citizen Science is a valuable way to both generate scientific data and to engage and educate a broad audience. Some areas of biology such as astronomy and ornithology have conducted multiple successful citizen science projects over the years. Surprisingly, there are not many citizen science projects in microbiology even though microbes are of interest to the majority of the public, as well as being tractable for these kinds of studies. This session will focus on citizen science in microbiology. This session will examine the diversity of Citizen Science projects, outline what makes a successful project, and highlight examples of past, current and future Citizen Microbiology projects. Speakers will also provide details on overcoming challenges in Citizen Science (e.g., visualization, permissions, privacy, standardization, informed consent). Our belief is that more projects, throughout the different domains of microbiology, could benefit from incorporating a citizen science component. Having this session at the General Meeting will help bring together people interested in this topic, as well as fostering collaboration on existing and future citizen science projects.
Sunday May 19 at the American Society for Microbiology General Meeting in Denver.  Register here.

Sampling the Wild Microbial Life of My Home

Just finally got around to doing the sampling of my house for the Wild Life of Our Homes microbial sampling project.

I signed up online, got a kit, got a registration code, and did the sampling today.  I swabbed the exterior door frame, an interior door frame, the kitchen counter and my pillow case.  Plus as a bonus, my 7 year old daughter helped – learning a bit about microbial sampling and also taking pictures of me at work (and a few of herself).

https://picasaweb.google.com/s/c/bin/slideshow.swf

So many cool Citizen Microbiology projects going on now. Some information about them is here but I need to update the links there.

Guest post: uBiome puts microbiome science in the hands of the people

It is a fascinating time to be doing microbiology. One of the latest occurrences is the spread of work on the human microbiome and even more recently the launching of several crowdfunding / citizen science efforts in this area. (Full disclosure – I am a collaborator on one of these efforts – the American Gut Project).  Another one of these efforts is a startup called uBiome. After seeing the announcement of their launch I asked Zac Apte, one of the founders, if he would be interested in writing a guest post for my blog on what they are doing. And, well, he agreed. And it is below (the post title “uBiome puts microbiome science in the hands of the people is from him too – I added the pic).


uBiome puts microbiome science in the hands of the people

Most people think “germs” is a dirty word. That’s what we’re taught since preschool. But the truth is that microbes aren’t just good or bad — it’s a lot more complicated than that. We are surrounded by microbes (on and inside of us) that form a complex ecosystem that supports and nourishes our health.

uBiome (www.indiegogo.com/ubiome) is a citizen science startup focused on allowing people direct access to this cutting ed research. By amassing a large set of microbiome samples along with health and lifestyle data, we will perform a microbiome-wide association study, examining specific traits as well as diseases such as diabetes, heart disease, hypertension, and depression in the context of the human microbiome.

We hope participants will join our community and track themselves in the long term — as you change your diet or exercise regime, begin taking a new medication, such as an antibiotic, or simply as you age. Now is a great time for a first data point.

Finally, we’re not just polling people for their poop. We’re also polling them for their creativity in scientific research. When our first dataset goes live, we’re going to ask our citizen scientists to form their own cohorts and we’ll empower them (statistically speaking) to test their own hypotheses. That’s our vision.

Our team has expertise in metagenomics as well as roots in population genetics, computer science, and network mathematics. We also have a team of scientific advisors which includes inventor and MacArthur Genius award winner Dr. Joseph DeRisi, biotechnology pioneer and inventor of the recombinant Hepatitis B vaccine Pablo Valenzuela, as well as doctors, bioinformaticians, and researchers.

We really appreciate Jonathan Eisen reaching out to give us this opportunity to say hello on the Tree of Life blog — and we look forward to engaging with you!

By Zac, Will and Jessica – the uBiome team

American Gut Project: Food, crowd sourcing, citizen science, open science, and MICROBES – what could be better?

A press release just came out announcing the American Gut Project: New public gut bacteria study expected to reach around world | University of Colorado Boulder.  From Rob Knight, Jeff Leach and others this project aims to engage the public in a large scale study of the connection between diet and the human gut microbiome.  Read more about it in the press release and I am sure more will come out soon.  Full disclosure – I have agreed to be a collaborator on the project – though as a fully open project I think pretty much anyone could be a collaborator.  Anyone this is definitely worth checking out.

As an aside – this is not the only crowd sourcing microbiome project out there.  I just became aware of another one called uBiome and I am working on getting a guest blog post from the organizers.  The American Gut project has got dozens of the major players in microbiome research involved.  And with Rob Knight being one of the key players one can expect it to big, cutting edge things.  Not sure about the scope / plans of uBiome but hopefully we will find out more soon.

Notes on #UCDavis Citizen Microbiology Meeting #UCDCitSci

We had a meeting at UC Davis on “Citizen Microbiology” from 1/23-1/24. It was a small meeting funded via my microBEnet project which itself is supported by a grant from the Alfred P. Sloan Fundation. The meeting was held at UC Davis – participants stayed at the new Hyatt on campus. We met in the new Conference Center. Participants at the meeting were me, David Coil (post doc in my lab), Paula Olsiewski (from the Sloan Foundation), Holly Bik (post doc in my lab), Darlene Cavalier (founder of ScienceForCitizens.Net), Dan Smith from Argonne National Lab, Denneal Jamison from UC Davis, Holly Menninger from NC State, Noah Feirer from CU Boulder, Josh Neufeld from Waterloo, Jason Bobe from The Personal Genome Project, Tom Bruns form UC Berkeley, Madhu Katti from Fresno State, Chris House from Penn. State, and Patrik D’haeseleer (from Lawrence Livermore National Lab).
Below is a “Storification” I made of the tweets and links from the meeting.

http://storify.com/phylogenomics/uc-davis-citizen-microbiology-meeting-ucdcitsci.js[<a href=”http://storify.com/phylogenomics/uc-davis-citizen-microbiology-meeting-ucdcitsci” target=”_blank”>View the story “UC Davis Citizen Microbiology meeting #UCDCitSci” on Storify</a>]

Crosspost from http://microbe.net – fun stuff from Rob Dunn

I am cross-posting this from the microBEnet blog I co-write:
I am enjoying the posts to the Scientific American Blogs by Rob Dunn on his and other Citizen Science project(s) and I thought I would share here.
If you do not know about Rob Dunn’s projects, well, you should.  I am particularly fascinated by “The Wild Life of Your Homes” which relate to the above posts.  He does some other fascinating projects too like “School of Ants” and “Wild Life of Your Body“.  Completely brilliant stuff worth checking out.


More on the Bioweathermap project #NotAboutWeather #ItsAboutMicrobes #AndMoney #CitizenMicrobiology

Just a mini post here about Bioweathermap.  I had posted a mini post about this project in July: Desperate to know what microbes are on your money? This project is for you (with some cool side science benefits).  I got reminded about this by this PLoS Blog: DIY Science at #SciBarSpace 2 | The Official PLoS Blog.  The PLoS blog discusses a talk by Jason Bobe about Bioweathermap.

Bioweathermap is not the most accurately named project but it is pretty cool.  From their site:

The BioWeatherMap initiative is a global, grassroots, distributed environmental sensing effort aimed at answering some very basic questions about the geographic and temporal distribution patterns of microbial life. Utilizing the power of high-throughput, low cost DNA sequencing and harnessing the drive of an enlightened public we propose a new collaborative research approach aimed at generating a steady stream of environmental samples from many geographic locations to produce high quality data for ongoing discovery and surveillance. Our approach will provide a unique opportunity to engage the public in the scientific research process while we address fundamental questions such as “How diverse is the microbial life around us?” and “How do microbial communities in different habitats change over time?” and “How can advanced sequencing technologies best be utilized to address issues in biodiversity, public health, and biosurveillance?”

In other words, it is about microbes (suggestion to them – it might be good to have something about microbes in the title of the project – maybe “microbioweathermap” or something like that).  Anyway, to do the project they have been collecting dollar bills from various people:

From PLoS Blog.

And then characterizing the microbes on those bills.  I note – Jason collected the bill from me when we met at the book launch party for Thomas Goetz’s “The Decision Tree“.  Anyway – in essence this is a citizen microbiology project and it is worth checking out.  For more on it see:

Seems to me there are more and more Citizen Microbiology projects out there.  For some other posts of mine about CM projects (got to give them an abbreviation) see: